Vascular disorders

Vascular function in heart disease

1993 – 1995 Glasgow University, Dr C Hamilton

Study of interactions of cholesterol and calcium in isolated human blood vessels, and their role in the thickening and hardening of arteries, replacing experiments in rabbits with artificially induced disease.

Blood vessel inflammation

1995 – 1998, St George’s Hospital, London, Dr H Parry & Dr G Whitley

Development of human blood vessel cell lines for studying vascular inflammation in the test-tube, and replace experimental studies in mice, rats and rabbits.

Blood vessel surgery

1996 – 1998 Northern General Hospital, Sheffield, Mr P Chan & Dr S Sherriff.

Application of ultrasound probe and imaging technology to study vascular surgical technique in patients undergoing heart by-pass operations. Replacing experimental surgery on rabbits, dogs and baboons.

Blood vessel repair

The June Hall Award for Humane Research
1990 – 1993 Cambridge University, Dr T-P Fan & A Wren

Culture of human blood vessel cells for investigation of blood vessel growth and repair in the test-tube. Abnormal blood vessel growth plays in role in many serious diseases, including cancer, atherosclerosis, heart disease, rheumatoid arthritis and diabetic blindness. An alternative to experiments on rats, mice, rabbits and guinea pigs.

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