Medical research
- Ageing
- Alzheimer's disease
- Asthma
- Brain signalling
- Cancer (breast)
- Cancer (lung)
- Cancer (skin)
- Cancer (brain)
- Cancer (general)
- Cataracts
- Cystic fibrosis
- Diabetes
- Diet and health
- Drug clearance
- Drug metabolism
- Epilepsy
- Foetal studies
- Heart disease
- HIV
- Huntington's disease
- Intestinal infections
- Kidney failure
- Liver disease
- Lung diseases
- Multiple sclerosis
- Meningitis
- Migraine
- Orthodontics
- Pain studies
- Parkinson's disease
- Rheumatism
- Sepsis
- Sleeping sickness
- Vascular disorders
- Whooping cough
- Wound healing
Brain signalling
Brain inflammation
2009 – 2012 Liverpool University, Professor T Solomon & Dr L Hubble
Development of a human blood brain barrier model in vitro to study viral encephalitis. To use as an alternative to invasive studies in mice, horses and non-human primates.
Brain circuitry
2008 – 2011 Durham University Dr A Ellison
Using TMS to investigate how different areas of the brain interact. An alternative to experiments in non-human primates such as macaques.
MEG Brain Scanner
2006 – 2011 Aston University, Prof P Furlong & Dr C Witton
Using MEG, a highly sophisticated type of brain imaging scanner, for non-invasive studies of the human brain in human volunteers. An alternative to experiments in dogs, monkeys and other non-human primates.
Brain circuitry
2006 – 2009 Oxford University, Dr H Johansen-Berg, Dr T Behrens & Prof D Higham
Development of non-invasive MRI diffusion imaging to study connections in the human brain, replacing experiments on rats and monkeys.
Neurochemistry
2004 – 2006 Aston University, Dr G Barnes & Dr S Hall
Combining non-invasive techniques MRS and MEG, to find safe, new ways to study the effect of drugs on the human brain. This is an alternative to experiments in rabbits, guinea pigs and pigs.
Migraine
2002 – 2004 Lancaster University, Dr E Chronicle
Using transcranial magnetic stimulation to discover a potential biobehavioural marker for migraine. Developing alternative techniques to experiments in non-human primates.
Brain damage
1998 – 2001 Oxford University, Dr V Walsh & Dr A Ellison
Demonstration of transcranial magnetic stimulation as a safe, non-invasive method of temporarily disrupting parts of the human brain, as an alternative to experiments in which monkeys are subjected to permanent brain damage.
Magnetoencephalography and epilepsy
1996 – 1999 Aston University, Prof G Harding
Use of non-invasive brain imaging technology, MEG (magnetoencephalography), to study changes in brain activity in epileptic patients, in particular visual triggers of photosensitive epilepsy. An alternative to studying induced seizures in restrained baboons, as well as cats and chickens.
Brain development
1985 Sheffield University, Dr E Carey
Study of brain cells in culture to investigate factors that influence the formation and survival of neurons, replacing experiments on fish, cats and dogs.