Cancer (general)

Cancer gene therapies

2000 – 2003 Glasgow University, Dr R Mairs & Dr M Boyd

Exploration in human tumour spheroids (three-dimensional cell cultures) of the potential for gene therapy to improve cancer radiation treatments, as an alternative to studies in rats or mice with implanted tumours.

Antibodies and cancer diagnosis

1997 – 2000 Newcastle University, Dr E Routledge & Dr B Angus

Investigation of in vitro production of antibodies for use in diagnosis and assessment of human breast and skin cancers, to replace standard production methods in mice.

Carcinogen susceptibility

1984 Nottingham University, Dr S Brown

Cell culture investigation of genetic susceptibility to chemically-caused cancers to replace the need for experimentation on mice and rats.

Cell-based cancer research

1982 Glasgow University, Dr I Freshney

Investigation of invasiveness of human cancer cells from lung biopsies, as an alternative to animals, such as mice and guinea pigs, with implanted tumours.

Improving childhood cancer therapies

1996 – 1998 Glasgow University, Dr T Wheldon

Improvement of treatment strategies for targeted radiotherapy of neuroblastoma and non-Hodgkins lymphoma by mathematical modelling, to by-pass animal tests on mice with implanted tumours.

Vitamin C and gastric cancer

1990 – 1993 Leeds University, Dr C Schorah

Use of gastric biopsy samples from volunteers to investigate the role of vitamin C in the prevention of stomach cancer, as an alternative to experiments on guinea pigs, rats, birds and monkeys.

Cancer drugs in human cells

1987 Cambridge University, Dr P Smith & Prof NM Bleehen

Evaluation of anti-cancer drugs by screening samples of human cells for DNA damage, as an alternative to animal studies in cats and dogs.

Lymphoma

1980 Edinburgh University, RJ Prescott

Computerised data storage and processing of pooled clinical information, to improve lymphoma treatments without resorting to animal experiments using mice, rats and fish.

Share |

Quick links