Diabetes

Diabetic microangiopathy

1996 – 1999 Manchester University, Dr R Boot-Handford

Development of an in vitro model of diabetic membrane thickening, a key process in the development of diabetic blindness and kidney damage, using the microscopic organism, Hydra. An alternative to experiments on rats and mice genetically altered to develop diabetes.


Diabetes and microcirculation

1995 – 1997 Exeter University, Dr A Shore

Application of laser Doppler perfusion imaging to study microcirculation in diabetic patients, replacing experiments on genetically altered mice and rats.


Pancreatic cell line and diabetes

1985 Aston University, Dr T Atkins

Establishment of a pure strain of pancreas cells that continue to produce insulin in culture. Removing the need to perform experiments on mice and rats genetically modified and bred to suffer from diabetes.


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