Kidney failure

Kidney failure

2000 – 2004 Guy’s Hospital, London, Dr A Simmonds & Dr A Marinaki

Identification of a toxic chemical that accumulates in the bloodstream of patients with kidney failure – an alternative to studies of animals, such as mice and pigs, with artificially induced kidney failure.

Kidney damage

1988 Surrey University, Dr P Bach

Provision of laboratory equipment for tissue culture studies to replace animals, such as mice and rats, in kidney toxicity tests.

Kidney cells

1984 – 1987 Surrey University, Dr P Bach

Evaluation of cultured kidney tubule cells as a replacement for animal tests to identify chemicals and drugs that cause kidney damage.

Renal toxicity in vitro

Co-funded with the Irish Health Research Board
2001 – 2004 University College, Dublin, Prof M Ryan & Dr T McMorrow

Development of a cell culture ‘model’ of the human kidney for studying the effects of chemicals and drugs in the test-tube, and detecting substances likely to cause kidney damage. An alternative to experiments on mice, rats, rabbits and pigs.

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